{"id":7363,"date":"2020-05-21T09:22:59","date_gmt":"2020-05-21T09:22:59","guid":{"rendered":"https:\/\/premioluisvaltuena.org\/?post_type=finalistas&#038;p=7363"},"modified":"2021-09-09T10:59:47","modified_gmt":"2021-09-09T10:59:47","slug":"kala-azar-black-fever","status":"publish","type":"finalistas","link":"https:\/\/premioluisvaltuena.org\/en\/finalistas\/2012\/david-rengel\/kala-azar-black-fever\/","title":{"rendered":"Kala azar, black fever"},"content":{"rendered":"\n<p>Leishmaniasis is a tropical parasitic disease caused by a variety of Leishmania that is transmitted by the bite of a certain type of sand fly. Visceral leishmaniasis, its most serious form, is also known as kala azar (black fever in Hindi).<\/p>\n\n\n\n<p>When a person becomes infected, his or her immune system is weakened and more vulnerable to other infections. Symptoms include anemia, weight loss, an enlarged spleen and lymphatic ganglia, and prolonged fever.<\/p>\n\n\n\n<p>Currently, one of the most usual treatments is .sodium stibogluconate (SSG), which requires a long course of treatment and is relatively toxic.  However, more and more resistance to this medication is being found, particularly in India where 65% of the cases occur.<\/p>\n\n\n\n<p>The most effective treatment is currently Liposomal amphotericin B, known by the brand name AmBisome. While this drug is highly effective, with low recurrence rates, is much less toxic, and requires a much shorter course of treatment than the drugs normally used, it is costly: roughly 300 euros per patient.<\/p>\n\n\n\n<p>Kala azar remains a forgotten disease when it comes to research and development of new treatments. Affordable, easy to use drugs are needed as well as rapid diagnostic testing in specific areas. The prices of the most effective drugs must be reduced. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Leishmaniasis is a tropical parasitic disease caused by a variety of Leishmania that is transmitted by the bite of a certain type of sand fly. Visceral leishmaniasis, its most serious form, is also known as kala azar (black fever in Hindi). When a person becomes infected, his or her immune system is weakened and more<\/p>\n","protected":false},"author":33,"featured_media":7386,"menu_order":369,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"edicion":[207],"class_list":["post-7363","finalistas","type-finalistas","status-publish","format-standard","has-post-thumbnail","hentry","edicion-207"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>David Rengel - Kala azar, black fever - Premio Luis Valtue\u00f1a<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/premioluisvaltuena.org\/en\/finalistas\/2012\/david-rengel\/kala-azar-black-fever\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"David Rengel - Kala azar, black fever - Premio Luis Valtue\u00f1a\" \/>\n<meta property=\"og:description\" content=\"Leishmaniasis is a tropical parasitic disease caused by a variety of Leishmania that is transmitted by the bite of a certain type of sand fly. 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